Sulfasalazine is converted by gut bacteria into sulfapyridine and the clinically active metabolite 5-aminosalicylic acid (5-ASA), and its e … Sulfasalazine-Induced Crystalluria Causing Severe Acute Kidney Injury Am J Kidney Dis. I really appreciate it. Information on the medication sulfasalazine (Azulfidine), a drug used for the treatment of ulcerative colitis, Crohn's disease, rheumatoid arthritis, or ankylosing spondylitis. Call your doctor if you also have yellowing of your eyes, brown urine, or stomach pain. Shame though as it really helped reduce pain. I often am able to resolve depression on my own. Flag this answer. I started leflunomide soon after & being doing ok on that, a little hair loss but I had that on MTX (which I'm still on) & that settled so would think the same will happen, otherwise no other side effects. Find patient medical information for Sulfasalazine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. As long as things are hygienic/clean. I found that the RA was causing night sweats, fevers, and weird anxiety. Throwing Up Skin Discoloration 10. Sulfasalazine, also known as Azulfidine® or Salazopyrin, produces a wide range of side effects, which correlate with the medication’s antibacterial, anti-inflammatory and immunosuppressive properties. Told me to keep on it and see how it went. I though 6 Sulfasalazine was max daily?, could it be that your maybe taking over the odds and they could be causing other problems? Sulfasalazine June 2017 Page 3 of 3 Blood disorders: leucopenia, thrombocytopenia. Don't hesitate to state your case if you see your GP & are diagnosed with depression. None of my clothes fit me!!! It is important to discuss any current medications or conditions with a physician before taking sulfasalazine. The immunosuppressive action of the medication might interfere with the chemicals, enzymes and cellular activity that produce natural immune responses. In patients with hypovolemia or dehydration, sulfasalazine may cause crystalluria and nephrolithiasis (stone formation) and contribute to urinary obstruction. @helixhelix... sorry to hear that. This is very demotivating to me as I am an outgoing person very calm and responsible, easy to get along with and now I can't even stand myself. That has not been a side effect for me. Some people say that Trazadone makes them sleepy. If I do notice a change from switching off the Sulfa, I will post back to let everyone know. I fit a similar profile to you and have had almost the exact same side effects. Also I am much calmer now as I am not as OCD or as fussy when things are not as perfect. During college, she was a reporter for a daily newspaper. Then, the more time someone spends gaming, the more his or her anxiety tends to increase. World Mental Health Day: 5 Tips for Coping with Covid Anxiety, Depression As 2020 drags on and the Covid-19 pandemic continues to ravage the … I even feel like it's not worth living. I also had muscle weakness as a side affect but I could live with it. These may be signs of liver problems. Thanks for submitting your experience. Depressed and anxiety. After a few weeks of Omega XL and Sulfasalazine I noticed my depression is more often and also realized that I am more tempered and cannot control my emotions. The OCD was a factor contributory to my RA coming on massive I believe all those years ago .. Based on a survey from the Anxiety Disorders Association of America, while only 9% of individuals are living with a diagnosed anxiety disorder, 40% experience ongoing stress or anxiety in their daily lives. Sulfasalazine side effects in this area may include bone marrow suppression, affecting red and white blood cells and potentially causing numerous types of blood disorders that result in anemia. Sulfasalazine is one of those meds that is used for different conditions & although we may have some members here who also have colitis you'll probably find the Crohns & Colitis site members will welcome & help you more specifically, especially with their experiences of your new med. And as for multi-tasking, well forget it! Then I found this site. For anyone being advised to take it, I don't want to scare you off, but for whatever reason the drug does have this adverse side effect in some of us and it is quite detrimental. Thank you for the follow up reply Abe22. Monitor renal function, including urinalysis, periodically throughout sulfasalazine treatment. Some gastric symptoms may be minimized by using enteric-coated tablets. Nervous tissue involvement may produce inflammation and pain along with hearing disturbances, hearing loss or lack of physical coordination. Some side effects include discolored urine, nausea, an increased likelihood of developing blood disorders, meningitis and hallucinations. WebMD takes a look at many factors that can create symptoms of an anxiety disorder. Sulfasalazine side effects in this area may include bone marrow suppression, affecting red and white blood cells and potentially causing numerous types of blood disorders that result in anemia. Sulfasalazine may cause sulfhemoglobinemia. So not quite the same as you, but a similar thing in that there's now a layer of fluff between me and the world. It is considered by some to be a first line treatment in rheumatoid arthritis. Sulfasalazine usually causes your urine and perspiration to take on an orange colour. Read more about the prescription drug sulfasalazine (Azulfidine). I started taking Sulfasalazine (8 tabs per day) ~6 month ago for Colitis. Loss Of Appetite 8. How Covid-19 Has Changed Grieving—And What That Means For Our Mental Health Less likely to snooze!! I think I am going to stop taking it straight away as I need to be able to focus at work & it's making it almost impossible. Now I'm wondering if I'm one of the lucky, rare few who don't play nice with this med. I hope as you need help it's asked of your Rheumy, that he's understanding & realises just how it's affecting you. Sulfasalazine delayed-release (Azulfidine EN-tabs) is also used to treat rheumatoid arthritis in adults and children whose disease has not responded well to other medications. Check with your doctor immediately if any of the following side effects occur while taking sulfasalazine: More common. Sulfasalazine is in a class of medications called anti-inflammatory drugs. Hope your doc/consultant can throw some light on the matter and you don't have to come off it if it is working so well for the colitis. She said that pharmacies and literature often state that 6 tabs is the daily max, but that in practice, they few 8 tabs as the daily max. This leads to a higher chance of infections, and must be monitored closely with regular blood tests. At any rate, I've just asked my doctor to switch my meds so I can experiment. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Consult psychiatrist can be treated easily. These are normal changes and do not mean you are having a reaction to the medicine. This will wash out of most clothing, but will stain some nylon fabrics. What's making you so anxious? Feel Like Throwing Up 5. Sulfasalazine can also turn your tears or your urine orange. Cite this article Stomach Cramps 11. Commonly used to treat rheumatoid arthritis and ulcerative colitis, sulfasalazine side effects also include adverse reactions, such as skin reactions, asthma and liver complications, in persons having certain medication sensitivities or preexisting medical conditions. Adequate fluid intake must be maintained in a treated patient in order to prevent crystalluria and stone formation. All anxiety-related problems share 4 common features: The anxiety is often an inexplicable fear or preoccupation that interferes with the child's or teen's ability to enjoy life or to complete daily routines or to do the things they are expected to do. Rash / stomatitis: withhold and discuss with specialist if severe or persistent. Side Effects. I am feeling the same way. Several potentially dangerous side effects have been reported rarely with sulfasalazine. Find patient medical information for Sulfasalazine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Sulpha was a fantastic med for me for 8 - 9 years for RA with no side effects to make me stop it. I then went back to my rheumy who took me off it straight away & said feeling that bad was no,way to treat me! "Brain fog" is something that is mentioned quite often on here and is something that we come across talking to people on the helpline as well. Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).. Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Thanks nomoreheels... didn't realize this was a RA specific site. Fever Caused By Administration Of A Drug 2. 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